Coping with climate change, the Mekong River Delta of Viet Nam is in the need of rice varieties with short growth durations (90-120 days), good tolerance to salinity (12-19 dSm-1), good resistance to brown plant hopper, and good grain quality. Nang Quot Bien is a seasonal rice with very good tolerance to salinity from 12 to 15 dSm-1. However, its maturity duration is quite long (150-170 days). Therefore, Nang Quot Bien’s maturity duration was shortened by temperature shock mutagen at 500 C for 5 minutes. Mutated lines were tested in terms of salinity tolerance according to IRRI method (1997), grain quality, brown plant hopper resistance, and pure line test by SDS-PAGE protein electrophoresis. Results at the M4 generation showed that two elite lines NQBDB 1-2-1-1 and NQBDB 2-1-6-3 with short maturity (≤110 days), final height <120 cm, low amylose content <20%, resistance to brown plant hopper, lodging resistant. Particularly, the two lines could tolerate to 19 dSm-1 (scale 5) and adapt well with the model of shrimp-rice.