Breeding rice for salt tolerance, short maturity duration, high grain quality, and good adaption to climate change is the most important problem in the Mekong Delta. Nang Tet rice variety collected in Thanh Phu district, Ben Tre province was used as a source of research materials. 100 seeds at germination stage was treated at 50°C for 5 minutes. Subsequently, the treated seeds together with the control were propagated  from M1 to M3 generations in the green house condition; critical selection was based on short-maturity individuals (<110 days), amylose content <20% and salt tolerance in Yoshida media 12-14‰. Results showed that 20 induced useful dominant mutation individuals had good traits such as short-maturity duration (95-100 days), salt tolerance at 12‰ (level 3), and 14‰ (level 5); low amylose content (9.65-14.54%), gelatinisation  at level 3, gel consistency at level 1; those were better than that of the control (180 days, salt tolerance at 12‰ (level 3), and 14‰ (level 5), amylose content of 20-25%, gelatinisation at level 1, gel consistency at level 3). Among them, eight individuals that gave the highest potential yield (35.35-65.08 g/plant) compared with the control (33.69 g/plant) was selected as good candidates to develop salt tolerant and good quality rice varieties.