In this study, authors propagated Curculigo orchioides Gaertn plants using the apical meristem culture method. The results indicated that: the most appropriate medium for multiplication of shoots was the MS medium supplemented with 30 g/1 sucrose + 5.5 g/1 agar + 200 ml/l coconut water + 1 g/l activated charcoal + 1.5 mg/l TDZ + 0.5 mg/l IBA + 1.0 mg/l AgNO3 + 50 mg/l Spirulina algae, with the results of 20.8 shoots/ explant and 5.2 leaves/plantlet after 6 weeks of culture. Root formation of shoots carried out on the MS medium supplemented with 30 g/1 sucrose + 5.5 g/1 agar + 200 ml/l coconut water + 1 g/l activated charcoal + 0.5 mg/l IBA gave the best result. In nursery, a mixture of humus + coconut fiber powder (70:30 ratio) was regarded as the best subtrate due to the high survival rate of plantlets (98%) and healthy plantlets (16.60 cm high with 6.9 leaves and 6.3 new roots/a plantlet) at 10 weeks after planting.